Our goal in founding Detraxi was to enhance organ preservation and cell culturing at room temperature and through cryopreservation. As our studies involving cells, tissues, and organs proceeded, it became clear that our proprietary technology had far broader applications and led us to develop novel therapies for the well-being of both humans and animals.FIND OUT MORE
One of the greatest challenges facing
emergency response teams is the
immediate availability of
the right blood type,
enabling patients to be stabilized for
long enough to receive treatment for
what can be survivable injuries.
The use of blood-based
products is the only
date for severe
The average waiting time for a
deceased donor kidney transplant
is approaching 3 years, and that for
heart transplants 18 months.
Each year, more patients are placed on the waiting lists
than receive transplants, causing the waiting time to
increase. With such constraints, preservation of organs
for transport between centers is crucial.
A key constraint in tissue and
organ transplants is that
solutions have barely
moved on since their
development in the late 1980's.
The critical issue with organ engineering
outside of the body is the limited
availability of human cells,
a suitable matrix with the same composition
and architecture of the target tissue, and
the ability to maintain the
viability of the organ without a blood supply.
Prepared stem cells are currently
being frozen in order to preserve
them. However, the temperature which frozen
cells are stored will affect their viabilitu. for example,
storage at-80oC may permit slow chemical reactions
(due to small amounts of unfrozen water). which will
eventually result in cell death.
Formaldehyde, a highly toxic poison, is
used as a 10% neutral buffered formalin,
the most widely used universal
fixative for preserving
organs and tissues.
An alternatives to Formaldehyde is
Clutaraldehyde, which although
widely used as a fixative for
standard electron microscopy.
has a slow penetration, needs periodic purification to
maintain functional aldehyde levels and therefore is
greatly limited as a bilogical fixative.